DIPG / DMG Clinical Trials

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Trials current as of: 2022-12-03
Viewing 87 clinical trials across 122 countries:

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Clinical Trial
Sponsor
Country
United States of America
National Institutes of Health Clinical Center (CC)
France
Gustave Roussy, Cancer Campus, Grand Paris

Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0
Last Updated: 2022-11-29
Originally Posted: 2022-07-25

United States of America
Chimerix

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
Last Updated: 2022-11-28
Originally Posted: 2022-09-27

Australia Israel Netherlands United States of America
University of California, San Francisco

Combination Therapy for the Treatment of Diffuse Midline Gliomas
Last Updated: 2022-11-18
Originally Posted: 2021-08-10

Australia Austria Canada Germany Italy Korea, Republic of United States of America
Blueprint Medicines Corporation
United States of America
Ann & Robert H Lurie Children's Hospital of Chicago
Canada
University of Calgary
United States of America
Baylor College of Medicine

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)
Last Updated: 2022-11-08
Originally Posted: 2019-09-20

Belgium
University Hospital, Antwerp
United States of America
SonALAsense, Inc.
United States of America
Pediatric Brain Tumor Consortium

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas
Last Updated: 2022-11-01
Originally Posted: 2020-02-27

United States of America
University of California, San Francisco
United States of America
National Cancer Institute (NCI)

Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors
Last Updated: 2022-10-19
Originally Posted: 2018-07-24

United States of America
Bexion Pharmaceuticals, Inc.
United States of America
Blueprint Medicines Corporation

A Drug-drug Interaction Study of Avapritinib and Midazolam
Last Updated: 2022-09-25
Originally Posted: 2021-05-27

United States of America
Augusta University
Switzerland United States of America
University of California, San Francisco
United States of America
Nationwide Children's Hospital
United States of America
Children's Hospital Medical Center, Cincinnati
China
Second Affiliated Hospital of Nanchang University
France
Institut Curie

AsiDNA Children, Adolescents and Young Adults
Last Updated: 2022-09-02
Originally Posted: 2021-12-16

United States of America
Children's National Research Institute

Multi-antigen T Cell Infusion Against Neuro-oncologic Disease
Last Updated: 2022-08-30
Originally Posted: 2018-08-28

United States of America
Aminex Therapeutics, Inc.

Oral AMXT 1501 Dicaprate in Combination With IV DFMO
Last Updated: 2022-08-12
Originally Posted: 2022-08-10

Australia Canada Germany Netherlands United Kingdom United States of America
Nationwide Children's Hospital
United States of America
University of California, San Francisco
United States of America
Pediatric Brain Tumor Consortium

Phase I Study of APX005M in Pediatric CNS Tumors
Last Updated: 2022-08-08
Originally Posted: 2017-12-15

United States of America
Emory University

AflacST1901: Peds WP1066
Last Updated: 2022-07-24
Originally Posted: 2020-04-02

China
Beijing Tiantan Hospital

Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma
Last Updated: 2022-07-18
Originally Posted: 2021-02-03

United States of America
National Institutes of Health Clinical Center (CC)
United States of America
Stanford University
Germany
University of Göttingen

International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)
Last Updated: 2022-06-02
Originally Posted: 2017-08-04

United States of America
Baylor College of Medicine
India
Tata Memorial Centre
United States of America
Actuate Therapeutics Inc.

9-ING-41 in Pediatric Patients With Refractory Malignancies.
Last Updated: 2022-04-26
Originally Posted: 2020-01-20

United States of America
Wake Forest University Health Sciences

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy
Last Updated: 2022-04-20
Originally Posted: 2021-04-06

United States of America
Northwell Health

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Last Updated: 2022-04-05
Originally Posted: 2013-04-16

United States of America
Emory University

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors
Last Updated: 2022-04-01
Originally Posted: 2015-12-15

United States of America
Columbia University

CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas
Last Updated: 2022-03-08
Originally Posted: 2020-02-07

United States of America
Chimerix
United States of America
Nationwide Children's Hospital
United States of America
University of Colorado, Denver

Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma
Last Updated: 2022-01-31
Originally Posted: 2016-11-29

United States of America
Mayo Clinic
Australia Canada New Zealand
University of Calgary

Re-Irradiation of Progressive or Recurrent DIPG
Last Updated: 2021-12-14
Originally Posted: 2017-04-19

United States of America
Ann & Robert H Lurie Children's Hospital of Chicago

Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells
Last Updated: 2021-11-03
Originally Posted: 2021-11-03

United States of America
Children's National Research Institute
United States of America
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Italy
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Study of Re-irradiation at Relapse Versus RT and Multiple Elective rt Courses
Last Updated: 2021-09-03
Originally Posted: 2018-05-14

United States of America
University of Cincinnati

Hypofractionated Radiotherapy for Recurrent DIPG
Last Updated: 2021-07-01
Originally Posted: 2019-02-12

Austria
Georg-August-Universität Göttingen, Stiftung Öffentlichen Rechts, Universitätsmedizin Göttingen
United States of America
Weill Medical College of Cornell University
Italy
ENTE OSPEDALIERO OSPEDALI GALLIERA

Diagnostic And Clinical Value Of 64cucl2 In Hgg/dipg
Last Updated: 2021-04-16
Originally Posted: 2021-04-16

Australia
Dr. David Ziegler
China
Shenzhen Geno-Immune Medical Institute

Immune Modulatory DC Vaccine Against Brain Tumor
Last Updated: 2020-06-10
Originally Posted: 2019-04-11

Germany
Georg-August-Universität Göttingen, Stiftung Öffentlichen Rechts, Universitätsmedizin Göttingen
France
Gustave Roussy, Cancer Campus, Grand Paris

Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication
Last Updated: 2018-07-20
Originally Posted: 2014-08-29

Netherlands
VU University Medical Center

11c-erlotinib Brain Uptake In Diffuse Intrinsic Pontine Glioma Imaged By Pet
Last Updated: 2018-05-04
Originally Posted: 2018-05-04

Netherlands
Gustave Roussy

Biological Medicine For Diffuse Intrinsic Pontine Glioma (dipg) Eradication
Last Updated: 2017-08-01
Originally Posted: 2017-08-01

Sweden
Gustave Roussy

Biological Medicine For Diffuse Intrinsic Pontine Glioma (dipg) Eradication
Last Updated: 2016-06-22
Originally Posted: 2016-06-22

Denmark
Gustave Roussy

Biological Medicine For Diffuse Intrinsic Pontine Glioma (dipg) Eradication
Last Updated: 2015-09-16
Originally Posted: 2015-09-16

Netherlands
VU University Medical Center

A Comprehensive And Targeted Therapy Approach In Pediatric Malignant Pontine Gliomas
Last Updated: 2010-06-09
Originally Posted: 2010-06-09

Content courtesy of clinicaltrials.gov, clinicaltrialsregister.eu, and anzctr.org.au