DIPG / DMG Clinical Trials

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Trials current as of: 2022-08-19
Viewing 80 clinical trials across 23 countries:

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Clinical Trial
Sponsor
Country
United States of America
United States of America SonALAsense, Inc.
United States of America
United States of America Aminex Therapeutics, Inc.

Oral AMXT 1501 Dicaprate in Combination With IV DFMO
Last Updated: 2022-08-12
Originally Posted: 2022-08-10

Australia Canada Germany Netherlands United Kingdom United States of America
Australia Canada Germany Netherlands United Kingdom United States of America Nationwide Children's Hospital
United States of America
United States of America University of California, San Francisco
United States of America
United States of America Pediatric Brain Tumor Consortium

Phase I Study of APX005M in Pediatric CNS Tumors
Last Updated: 2022-08-08
Originally Posted: 2017-12-15

United States of America
United States of America National Cancer Institute (NCI)

Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors
Last Updated: 2022-08-06
Originally Posted: 2018-07-24

United States of America
United States of America Ann & Robert H Lurie Children's Hospital of Chicago
United States of America
United States of America University of California, San Francisco

Combination Therapy for the Treatment of Diffuse Midline Gliomas
Last Updated: 2022-08-02
Originally Posted: 2021-08-10

United States of America
United States of America Emory University

AflacST1901: Peds WP1066
Last Updated: 2022-07-24
Originally Posted: 2020-04-02

Austria Canada Germany Korea, Republic of United States of America
Austria Canada Germany Korea, Republic of United States of America Blueprint Medicines Corporation
United States of America
United States of America Nationwide Children's Hospital
China
China Beijing Tiantan Hospital

Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma
Last Updated: 2022-07-18
Originally Posted: 2021-02-03

United States of America
United States of America Augusta University
United States of America
United States of America National Institutes of Health Clinical Center (CC)
Switzerland United States of America
Switzerland United States of America University of California, San Francisco

Fimepinostat in Treating Brain Tumors in Children and Young Adults
Last Updated: 2022-07-05
Originally Posted: 2019-03-26

United States of America
United States of America Stanford University
United States of America
United States of America Bexion Pharmaceuticals, Inc.
Germany
Germany University of Göttingen

International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)
Last Updated: 2022-06-02
Originally Posted: 2017-08-04

Canada
Canada University of Calgary
United States of America
United States of America University of California, San Francisco
United States of America
United States of America Baylor College of Medicine
India
India Tata Memorial Centre
Switzerland United States of America
Switzerland United States of America University of California, San Francisco
United States of America
United States of America Actuate Therapeutics Inc.

9-ING-41 in Pediatric Patients With Refractory Malignancies.
Last Updated: 2022-04-26
Originally Posted: 2020-01-20

United States of America
United States of America Wake Forest University Health Sciences

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy
Last Updated: 2022-04-20
Originally Posted: 2021-04-06

United States of America
United States of America Northwell Health

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Last Updated: 2022-04-05
Originally Posted: 2013-04-16

United States of America
United States of America Emory University

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors
Last Updated: 2022-04-01
Originally Posted: 2015-12-15

United States of America
United States of America Columbia University

CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas
Last Updated: 2022-03-08
Originally Posted: 2020-02-07

United States of America
United States of America Chimerix

ONC201 in Pediatric H3 K27M Gliomas
Last Updated: 2022-03-01
Originally Posted: 2018-01-23

United States of America
United States of America Chimerix
United States of America
United States of America Nationwide Children's Hospital
United States of America
United States of America Baylor College of Medicine

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)
Last Updated: 2022-02-07
Originally Posted: 2019-09-20

United States of America
United States of America University of Colorado, Denver

Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma
Last Updated: 2022-01-31
Originally Posted: 2016-11-29

United States of America
United States of America Mayo Clinic
Australia Canada New Zealand
Australia Canada New Zealand University of Calgary

Re-Irradiation of Progressive or Recurrent DIPG
Last Updated: 2021-12-14
Originally Posted: 2017-04-19

United States of America
United States of America Ann & Robert H Lurie Children's Hospital of Chicago

Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells
Last Updated: 2021-11-03
Originally Posted: 2021-11-03

United States of America
United States of America Children's National Research Institute
United States of America
United States of America Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Belgium
Belgium University Hospital, Antwerp
Italy
Italy Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Study of Re-irradiation at Relapse Versus RT and Multiple Elective rt Courses
Last Updated: 2021-09-03
Originally Posted: 2018-05-14

United States of America United States of America
United States of America United States of America Children's National Research Institute

Multi-antigen T Cell Infusion Against Neuro-oncologic Disease
Last Updated: 2021-07-15
Originally Posted: 2018-08-28

United States of America
United States of America University of Cincinnati

Hypofractionated Radiotherapy for Recurrent DIPG
Last Updated: 2021-07-01
Originally Posted: 2019-02-12

United States of America
United States of America Children's Hospital Medical Center, Cincinnati
Austria
Austria Georg-August-Universität Göttingen, Stiftung Öffentlichen Rechts, Universitätsmedizin Göttingen
United States of America
United States of America Weill Medical College of Cornell University
Italy
Italy ENTE OSPEDALIERO OSPEDALI GALLIERA

Diagnostic And Clinical Value Of 64cucl2 In Hgg/dipg
Last Updated: 2021-04-16
Originally Posted: 2021-04-16

Australia
Australia Dr. David Ziegler
China
China Shenzhen Geno-Immune Medical Institute

Immune Modulatory DC Vaccine Against Brain Tumor
Last Updated: 2020-06-10
Originally Posted: 2019-04-11

Germany
Germany Georg-August-Universität Göttingen, Stiftung Öffentlichen Rechts, Universitätsmedizin Göttingen
France
France Gustave Roussy, Cancer Campus, Grand Paris

Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication
Last Updated: 2018-07-20
Originally Posted: 2014-08-29

Netherlands
Netherlands VU University Medical Center

11c-erlotinib Brain Uptake In Diffuse Intrinsic Pontine Glioma Imaged By Pet
Last Updated: 2018-05-04
Originally Posted: 2018-05-04

Netherlands
Netherlands Gustave Roussy

Biological Medicine For Diffuse Intrinsic Pontine Glioma (dipg) Eradication
Last Updated: 2017-08-01
Originally Posted: 2017-08-01

Sweden
Sweden Gustave Roussy

Biological Medicine For Diffuse Intrinsic Pontine Glioma (dipg) Eradication
Last Updated: 2016-06-22
Originally Posted: 2016-06-22

Denmark
Denmark Gustave Roussy

Biological Medicine For Diffuse Intrinsic Pontine Glioma (dipg) Eradication
Last Updated: 2015-09-16
Originally Posted: 2015-09-16

Netherlands
Netherlands VU University Medical Center

A Comprehensive And Targeted Therapy Approach In Pediatric Malignant Pontine Gliomas
Last Updated: 2010-06-09
Originally Posted: 2010-06-09

Content courtesy of clinicaltrials.gov, clinicaltrialsregister.eu, and anzctr.org.au