DIPG / DMG Clinical Trials
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Trials current as of: 2025-04-25
Combination Therapy for the Treatment of Diffuse Midline Gliomas
Last Updated: 2023-11-24
Originally Posted: 2021-08-18
Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)
Last Updated: 2023-11-20
Originally Posted: 2018-01-11
Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma
Last Updated: 2023-11-15
Originally Posted: 2018-11-13
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors
Last Updated: 2023-11-14
Originally Posted: 2018-02-15
Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations
Last Updated: 2023-11-08
Originally Posted: 2018-07-10
A Study of Lenvatinib (MK-7902) in Pediatric Participants With Relapsed or Refractory Solid Malignancies (MK-7902-013/E7080)
Last Updated: 2023-10-04
Originally Posted: 2020-06-25
Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
Last Updated: 2023-09-28
Originally Posted: 2013-08-14
Fimepinostat in Treating Brain Tumors in Children and Young Adults
Last Updated: 2023-08-18
Originally Posted: 2019-03-28
ONC201 in Pediatric H3 K27M Gliomas
Last Updated: 2023-08-15
Originally Posted: 2018-01-31
ONC201 in Adults With Recurrent H3 K27M-mutant Glioma
Last Updated: 2023-08-15
Originally Posted: 2017-09-27
Oral ONC201 in Recurrent GBM, H3 K27M Glioma, and Midline Glioma
Last Updated: 2023-08-15
Originally Posted: 2015-08-17
T Cells Expressing HER2-specific Chimeric Antigen Receptors(CAR) for Patients With HER2-Positive CNS Tumors
Last Updated: 2023-08-14
Originally Posted: 2015-05-13
Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma
Last Updated: 2023-08-14
Originally Posted: 2015-04-20
9-ING-41 in Pediatric Patients With Refractory Malignancies.
Last Updated: 2023-06-18
Originally Posted: 2020-01-23
Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma
Last Updated: 2023-05-17
Originally Posted: 2018-03-27
INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas
Last Updated: 2023-05-15
Originally Posted: 2020-03-04
Phase I Study of APX005M in Pediatric CNS Tumors
Last Updated: 2023-04-04
Originally Posted: 2018-01-04
Study of Re-irradiation at Relapse Versus RT and Multiple Elective rt Courses
Last Updated: 2023-03-24
Originally Posted: 2018-08-08
Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma
Last Updated: 2023-01-30
Originally Posted: 2021-06-03
Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma
Last Updated: 2023-01-13
Originally Posted: 2016-03-23
Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma
Last Updated: 2022-10-26
Originally Posted: 2020-05-14
Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)
Last Updated: 2022-02-14
Originally Posted: 2021-03-18