DIPG / DMG Clinical Trials
DIPG and DMG are complex diagnoses, and treatment options continue to evolve. Clinical trials may be one option to consider as you explore what comes next.
We've provided a pre-filtered search through www.clinicaltrials.gov to help you find trials that are currently recruiting or active for DIPG and DMG.
If you have questions about finding clinical trials that are available, please reach out and we are more than happy to help.
Please Note: The most accurate and up-to-date trial information can be found by accessing ClinicalTrials.gov using the link above.
Combination Therapy for the Treatment of Diffuse Midline Gliomas
Originally Posted: 2021-08-18
Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)
Originally Posted: 2018-01-11
Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma
Originally Posted: 2018-11-13
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors
Originally Posted: 2018-02-15
Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations
Originally Posted: 2018-07-10
A Study of Lenvatinib (MK-7902) in Pediatric Participants With Relapsed or Refractory Solid Malignancies (MK-7902-013/E7080)
Originally Posted: 2020-06-25
Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
Originally Posted: 2013-08-14
Fimepinostat in Treating Brain Tumors in Children and Young Adults
Originally Posted: 2019-03-28
ONC201 in Pediatric H3 K27M Gliomas
Originally Posted: 2018-01-31
ONC201 in Adults With Recurrent H3 K27M-mutant Glioma
Originally Posted: 2017-09-27
Oral ONC201 in Recurrent GBM, H3 K27M Glioma, and Midline Glioma
Originally Posted: 2015-08-17
T Cells Expressing HER2-specific Chimeric Antigen Receptors(CAR) for Patients With HER2-Positive CNS Tumors
Originally Posted: 2015-05-13
Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma
Originally Posted: 2015-04-20
9-ING-41 in Pediatric Patients With Refractory Malignancies.
Originally Posted: 2020-01-23
Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma
Originally Posted: 2018-03-27
INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas
Originally Posted: 2020-03-04
Phase I Study of APX005M in Pediatric CNS Tumors
Originally Posted: 2018-01-04
Study of Re-irradiation at Relapse Versus RT and Multiple Elective rt Courses
Originally Posted: 2018-08-08
Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma
Originally Posted: 2021-06-03
Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma
Originally Posted: 2016-03-23
Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma
Originally Posted: 2020-05-14
Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)
Originally Posted: 2021-03-18